Kris V Kowdley Selected Research

Biomarkers (Surrogate Marker)

1/2023	IL-31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH.
1/2023	Safety and Sustained Efficacy of the Farnesoid X Receptor (FXR) Agonist Cilofexor Over a 96-Week Open-label Extension in Patients With PSC.
1/2023	Geographical region and clinical outcomes of patients with primary biliary cholangitis from Western Europe.
12/2022	Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls.
5/2021	The Evolving Use of Biochemical Markers in the Management of Primary Biliary Cholangitis: Discussion.
5/2021	An Examination of the Evidence Behind Biochemical Markers in Primary Biliary Cholangitis.
5/2021	Relationship of ELF and PIIINP With Liver Histology and Response to Vitamin E or Pioglitazone in the PIVENS Trial.
1/2020	Emerging drugs for the treatment of non-alcoholic steatohepatitis: a focused review of farnesoid X receptor agonists.
12/2019	Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial.
11/2019	Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis.

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Kris V Kowdley Research Topics

Disease

84	Fibrosis (Cirrhosis) 06/2024 - 04/2002
56	Non-alcoholic Fatty Liver Disease 01/2024 - 08/2003
35	Liver Diseases (Liver Disease) 04/2024 - 05/2002
33	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 02/2024 - 11/2005
31	Infections 05/2021 - 04/2002
30	Iron Overload 02/2024 - 09/2003
27	Hemochromatosis (Bronze Diabetes) 12/2023 - 04/2003
23	Chronic Hepatitis C 01/2019 - 04/2002
22	Inflammation (Inflammations) 01/2023 - 08/2008
17	Hepatitis C 01/2018 - 04/2002
14	Hepatocellular Carcinoma (Hepatoma) 05/2024 - 07/2003
14	Sclerosing Cholangitis 01/2024 - 02/2008
13	Pruritus (Itching) 02/2024 - 03/2015
12	Liver Cirrhosis (Hepatic Cirrhosis) 11/2023 - 05/2009
12	Chronic Hepatitis B 04/2013 - 05/2002
11	End Stage Liver Disease 01/2021 - 02/2003
9	Alcoholic Fatty Liver 11/2023 - 01/2009
9	Neoplasms (Cancer) 04/2017 - 11/2002
8	Disease Progression 06/2023 - 04/2002
8	Fatty Liver 11/2019 - 01/2009
7	Cholestasis 11/2023 - 05/2012
7	Insulin Resistance 01/2022 - 09/2010
7	Fatigue 07/2021 - 04/2013
6	Nausea 11/2023 - 04/2013
6	Hemorrhage 01/2021 - 05/2002
5	Ascites 06/2024 - 03/2003
5	Varicose Veins (Varicose Vein) 05/2024 - 11/2005
5	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2023 - 01/2018
5	Obesity 07/2014 - 08/2003
4	Hyperferritinemia 01/2022 - 05/2004
4	Hepatic Encephalopathy 01/2021 - 09/2005
4	Liver Failure 01/2021 - 05/2002
4	Diabetes Mellitus 11/2019 - 05/2009
4	Anemia 01/2018 - 09/2012
4	Hepatitis B 08/2008 - 04/2003
3	Iron Deficiencies 07/2014 - 05/2004
3	Type 2 Diabetes Mellitus (MODY) 06/2014 - 11/2003

Drug/Important Bio-Agent (IBA)

56	IronIBA 02/2024 - 04/2002
29	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 11/2023 - 03/2004
22	Biomarkers (Surrogate Marker)IBA 01/2023 - 04/2002
22	Ribavirin (Virazole)FDA LinkGeneric 02/2019 - 04/2002
18	obeticholic acidIBA 11/2023 - 03/2015
15	Alkaline PhosphataseIBA 02/2024 - 09/2010
14	HepcidinsIBA 12/2023 - 02/2004
14	Alanine Transaminase (SGPT)IBA 12/2022 - 08/2008
14	SofosbuvirIBA 01/2017 - 04/2013
13	Ferritins (Ferritin)IBA 12/2023 - 04/2002
13	nasIBA 01/2022 - 01/2009
13	Antiviral Agents (Antivirals)IBA 02/2019 - 11/2005
12	Bile Acids and Salts (Bile Acids)IBA 03/2023 - 07/2010
11	InterferonsIBA 01/2018 - 04/2002
9	BilirubinIBA 12/2022 - 11/2005
8	Aspartate Aminotransferases (Aspartate Transaminase)IBA 12/2022 - 05/2010
8	EnzymesIBA 01/2020 - 04/2003
8	Protease Inhibitors (Protease Inhibitor)IBA 01/2017 - 09/2012
8	sofosbuvir drug combination ledipasvirIBA 01/2017 - 05/2014
7	Transaminases (Aminotransferases)IBA 08/2015 - 04/2002
6	Proteins (Proteins, Gene)FDA Link 04/2024 - 05/2005
6	cilofexorIBA 03/2023 - 01/2019
6	Triglycerides (Triacylglycerol)IBA 10/2021 - 11/2003
6	Vitamin E FDA LinkGeneric 05/2021 - 01/2009
6	paritaprevirIBA 02/2019 - 01/2013
6	NucleotidesIBA 01/2017 - 07/2011
6	Transferrin (beta 2 Transferrin)IBA 03/2014 - 04/2002
6	Lamivudine (Epivir)FDA Link 01/2007 - 05/2002
5	Pioglitazone (Actos)FDA Link 05/2021 - 03/2007
5	acceleratory factor from growth hormone (AcG)IBA 02/2021 - 05/2015
5	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 02/2020 - 09/2010
5	dasabuvirIBA 02/2019 - 01/2013
5	Ritonavir (Norvir)FDA Link 02/2019 - 01/2013
4	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 11/2023 - 01/2020
4	LipidsIBA 10/2021 - 08/2016
4	Glucose (Dextrose)FDA LinkGeneric 10/2021 - 01/2010
4	CollagenIBA 01/2021 - 01/2020
4	Insulin (Novolin)FDA Link 01/2021 - 01/2010
4	LigandsIBA 12/2019 - 03/2015
4	ombitasvirIBA 02/2019 - 01/2014
4	Dietary IronIBA 01/2016 - 12/2003
4	CopperIBA 01/2014 - 12/2003
4	entecavir FDA Link 04/2013 - 01/2007
4	Hepatitis B e AntigensIBA 09/2012 - 04/2003
3	Rifaximin (L 105)FDA Link 06/2024 - 08/2010
3	MicroRNAs (MicroRNA)IBA 06/2023 - 03/2012
3	AdiponectinIBA 10/2021 - 02/2005
3	cenicrivirocIBA 09/2021 - 01/2018
3	selonsertibIBA 07/2021 - 01/2019
3	Drug CombinationsIBA 07/2021 - 01/2019
3	Interleukin-6 (Interleukin 6)IBA 05/2021 - 07/2014
3	DiureticsIBA 01/2021 - 03/2003
3	RNA (Ribonucleic Acid)IBA 01/2021 - 05/2013
3	SodiumIBA 01/2021 - 03/2003
3	metal transporting protein 1 (ferroportin)IBA 01/2021 - 02/2005
3	Protons (Proton)IBA 01/2019 - 01/2007
3	daclatasvirIBA 11/2016 - 04/2015
3	ledipasvirIBA 01/2016 - 05/2014

Therapy/Procedure

54	Therapeutics 09/2023 - 05/2002
35	Liver Transplantation 05/2024 - 05/2002
4	Transplantation 02/2020 - 11/2005
4	Duration of Therapy 03/2017 - 07/2007
3	Cell Transplantation 01/2016 - 02/2009